AbbVie Returns OSE-230 Development Rights After $48M Acquisition

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AbbVie handed back preclinical and Phase I development of OSE-230 to OSE Therapeutics under a December 2025 amendment after acquiring global rights in February 2024 for $48 million. The move follows OSE’s pause of OSE-230 work to focus on late-stage candidates, cutting AbbVie’s R&D exposure to early-stage inflammation assets.

1. AbbVie’s $48M Acquisition of OSE-230

AbbVie acquired global rights to OSE-230 in February 2024 for $48 million, initially overseeing its preclinical and Phase I development in partnership with OSE Therapeutics.

2. Amendment Returns Development Rights

Under a December 2025 amendment, AbbVie relinquished preclinical and Phase I responsibilities for OSE-230 as OSE Therapeutics refocused its pipeline on later-stage assets, thereby reducing AbbVie’s exposure to early-stage inflammatory research.

Sources

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