Alnylam posted Q2 revenue of USD 1.29 billion, up 67% year over year, as net product revenues rose 74% to USD 1.17 billion.
GAAP net income swung to USD 164.49 million; GAAP EPS was USD 1.23.
AMVUTTRA net product revenues more than doubled to USD 1.01 billion, lifting total TTR net product revenues 89% to USD 1.03 billion.
Guidance and management commentary
Full-year 2026 TTR net product revenue guidance was cut to USD 4.2 billion-USD 4.5 billion; total net product revenue outlook was lowered to USD 4.7 billion-USD 5.1 billion.
CEO Yvonne Greenstreet cited normalized second-line volume after early pent-up demand.
Alnylam signed an exclusive AMVUTTRA China deal with BeOne.