Artelo Biosciences Eyes Q4 2026 Phase 1 Dosing with $10.3M Cash

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Artelo Biosciences reported a net loss of $3.0 million ($4.00/share) in Q1 2026 and held $10.3 million cash/investments, following a $0.8 million R&D expense. The company plans to initiate ART26.12 multiple ascending dose trial in Q4 2026 and is exploring ART27.13 expansion after interim Phase 2 CAReS data showing >6% weight gain.

1. Q1 2026 Financial Results

Artelo reported a net loss of $3.0 million, or $4.00 per share, for the quarter ended March 31, 2026, compared to a $2.4 million loss in Q1 2025. R&D expenses declined to $0.8 million from $1.4 million year-over-year, while G&A rose to $1.9 million from $1.0 million, and cash and investments totaled $10.3 million.

2. ART26.12 Phase 1 Progress

ART26.12 completed single ascending dose and food-effect cohorts with favorable safety and predictable pharmacokinetics. The company is preparing to launch the multiple ascending dose study in Q4 2026, targeting chemotherapy-induced peripheral neuropathy with a non-opioid, non-steroidal analgesic approach.

3. ART27.13 Phase 2 CAReS Update

Interim Phase 2 CAReS data in cancer-related anorexia patients showed mean weight gain over 6% at the top dose versus 5% loss on placebo, along with increases in lean body mass and physical activity. Strategic discussions are underway for next-stage development and additional indications, including GLP-1 companion therapy and a funded glaucoma study.

4. Balance Sheet and Partnerships

A recent capital raise bolstered the balance sheet, extending runway to support key clinical milestones through 2027. The company benefits from third-party research grants, notably a fully funded ART27.13 glaucoma trial, and is engaged in partnering negotiations to drive future value creation.

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