BioAge doses first patient in Phase 2 QUELL-DME trial of oral NLRP3 inhibitor BGE-102
BIOA•Phase 2 diabetic macular edema trial begins dosing
BioAge Labs began dosing the first participant in QUELL-DME, a Phase 2 trial of oral NLRP3 inhibitor BGE-102 for diabetic macular edema.
- Results have not been presented; topline data are expected in the second half of 2027.
- The study will assess whether daily oral treatment can improve vision, used alone or alongside standard anti-VEGF eye injections.
- Roughly 180 adults are enrolled in a randomized, controlled design with a 12-week treatment period.




