Bruker launches timsUltra AIP workflow to boost protein sequence coverage in proteomics studies
BRKR•Bruker unveiled timsUltra AIP and timsOmni workflows for proteomics applications. Multi-enzyme dia-PASEF on timsUltra AIP produced about 350,000 peptides per Parkinson’s brain sample, supporting about 14,500 isoforms.
1. New proteomics workflows
Bruker introduced timsUltra AIP and timsOmni workflows aimed at deeper proteomics coverage, targeted validation, glycoproteomics, structural proteomics and oligonucleotide analysis. ProteoScape converts PASEF discovery outputs into prm-PASEF target lists on the same timsTOF platform, while Spectronaut v21 transfer learning is positioned to speed adaptation to new acquisition modes without rebuilding models from scratch. timsOmni additions include mobility-resolved glycopeptide characterization above 30 Hz, HDX-MS integration and EDD-MS3 for complete RNA and DNA oligonucleotide coverage.
