Eli Lilly and Co climbed after lifting its annual revenue forecast.
Charles River Laboratories International climbed after lifting its annual profit forecast.
Wynn Resorts Ltd rose on a Q2 beat and UAE casino update.
Griffon Corp gained after quarterly profit topped estimates.
Kratos Defense & Security Solutions Inc jumped after a Q2 beat-and-raise report.
Amgen Inc jumped to a record high after hiking FY forecasts and reporting Q2 results that beat estimates.
U.S. stocks mixed near record highs
The S&P 500 and the Dow traded at all-time highs on Wednesday on hopes of a Middle East peace breakthrough, while the tech-heavy Nasdaq struggled to stay afloat, limited by a slide in SpaceX and AMD after upbeat forecasts issued by the companies failed to impress investors.
At 11:30 EDT, the Dow Jones Industrial Average was up 0.83% at 54,532.43. The S&P 500 was up 0.07% at 7,742.06, and the Nasdaq Composite was down 0.08% at 26,562.65.