Gilead Tops Q1 Estimates with 12% HIV, 28% Trodelvy Sales Growth

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Gilead reported Q1 adjusted EPS of $1.52, beating estimates of $1.46, and delivered revenue of $6.7 billion versus $6.65 billion expected, driven by a 12% increase in HIV drug sales and a 28% gain in Trodelvy sales. The company lowered its 2026 EPS guidance to $5.85–$5.95 from $6.10–$6.20, triggering a share pullback.

1. Q1 Financial Results

Gilead delivered adjusted EPS of $1.52 in the first quarter, surpassing the consensus forecast of $1.46, and reported revenue of $6.7 billion compared with expectations of $6.65 billion, underscoring strong operational execution.

2. HIV and Trodelvy Performance

The HIV franchise saw sales climb 12% year-over-year to approximately $3.1 billion, while cancer therapy Trodelvy recorded a 28% sales increase to roughly $550 million, together accounting for the bulk of top-line growth.

3. Guidance Revision

Management revised its full-year 2026 adjusted EPS outlook downward to a range of $5.85–$5.95 from a prior range of $6.10–$6.20, citing anticipated pricing pressures and increased investment in clinical development.

4. Market Reaction

Shares of Gilead fell by around 3% in after-hours trading as investors weighed the robust quarterly beat against the more conservative earnings outlook for the remainder of the year.

Sources

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