Grail publishes PATHFINDER 2 presentation on diagnostic workups after positive cancer screening tests
GRAL•Grail published a PATHFINDER 2 presentation on diagnostic evaluations after positive multi-cancer early detection tests. Signal-origin-guided evaluations identified 88% of cancers, while diagnostic resolution reached 94.8% among 290 evaluated participants, with a median time of 48 days.
1. PATHFINDER 2 findings
Grail said signal-origin-guided evaluations identified 88% of cancers, and the top two predicted cancer signal origins were accurate in 91% of cases. Diagnostic resolution reached 94.8% among 290 evaluated participants, with a median time of 48 days.
2. Procedures and PET-CT
Invasive procedures occurred in 91% of participants diagnosed with cancer, compared with 49.6% of those without cancer at 12 months. PET-CT after negative targeted evaluations found seven additional cancers among 65 participants.
