Incyte Reports 20% Q4 Revenue Growth to $780M, Launches Two Phase III Trials
Jakafi sales climbed 20% in Q4 2025, driving Incyte's overall revenue to $780 million. The company also kicked off Phase III studies for its JAK1 inhibitor itacitinib and FGFR inhibitor pemigatinib.
1. Q4 2025 Financial Performance
Incyte posted $780 million in revenue for Q4 2025, a 20% increase year-over-year. The growth was primarily driven by a 20% rise in Jakafi sales across its myelofibrosis and graft-versus-host disease indications.
2. Pipeline Advancement
The company initiated Phase III trials for its JAK1 inhibitor itacitinib in acute GVHD and FGFR inhibitor pemigatinib in cholangiocarcinoma. Management expects initial clinical data by late 2026.