Lantheus PET Tracer Yields 95% Sensitivity, Wins SNMMI Image of Year
LNTH•Lantheus' investigational PET tracer LNTH-2513 achieved 95% sensitivity and 92% specificity for proximal DVT in a 46-patient trial, detecting pulmonary embolisms in 22 cases without adverse events. The LNTH-2513 PET/CT image was named SNMMI Image of the Year, highlighting its thrombus-specific imaging capabilities.
1. SNMMI Image of the Year Award
The LNTH-2513 PET/CT image was honored as Image of the Year at SNMMI’s 2026 Annual Meeting, showcasing its ability to visualize acute thrombi across multiple vascular regions including deep veins, lungs, and cardiac vessels.
2. High Diagnostic Accuracy in DVT Trial
In a 46-patient open-label study of suspected lower-extremity DVT, LNTH-2513 achieved patient-based sensitivity of 95% and specificity of 92% for proximal clots, and demonstrated 96% positive and 90% negative agreement for distal clots versus venous ultrasound.
3. Safety Profile and Clinical Potential
LNTH-2513 detected pulmonary embolisms in 22 patients and was well tolerated with no drug-related adverse events, suggesting a promising thrombus-specific imaging tool that may improve detection in regions challenging for conventional ultrasound and support upcoming regulatory filings.
