Moderna-Merck melanoma vaccine leads race for first therapeutic cancer vaccine
MRNA•Major cancer vaccine candidates in clinical trials
Below is a list of major cancer vaccine candidates currently in clinical trials globally:
| Company | Vaccine name | Stage of development | Vaccine details |
|---|---|---|---|
| Moderna and Merck | mRNA-4157 (V940) | Late-stage | It uses mRNA technology tailored to the genetic profile of a patient's tumor and is administered alongside the immunotherapy drug Keytruda to help prevent recurrence in melanoma and lung cancer. |
| IO Biotech and Merck | Cylembio | Late-stage | The company is testing the vaccine, in combination with Merck's Keytruda, in patients with advanced melanoma. |
| Greenwich LifeSciences | GLSI-100 | Late-stage | The vaccine to prevent breast cancer from returning in patients who have already undergone surgery. It targets the HER2/neu protein, which is commonly expressed on breast cancer cells. |
| OSE Immunotherapeutics | Tedopi | Late-stage |
