Neumora Therapeutics posts corporate presentation on neuroscience drug development pipeline
NMRA•Preclinical NMRA-215 data showed weight loss
Preclinical NMRA-215 data showed up to 19% weight loss as monotherapy; up to 26% when combined with semaglutide.
Corporate presentation highlights three lead programs
Neumora outlined three lead programs across cardiometabolic, neurodegenerative, and neuropsychiatric disease, anchored by NMRA-215, NMRA-511, and NMRA-898.
- NMRA-215: NLRP3 inhibitor in obesity/CV risk. IND submission targeted for 4Q 2026; Phase 1 start planned by year-end 2026.
- NMRA-511: V1aR antagonist for agitation in Alzheimer’s disease. Multiple-ascending-dose extension data expected 4Q 2026; Phase 2 initiation planned by year-end 2026.
- NMRA-898: M4 modulator for schizophrenia. Phase 1 data expected in 2H 2026.




