NEXGEL Patch Cuts Laser Plume 95.6%, Lowers Pain Scores by 31%

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NEXGEL’s hydrogel patch cut laser plume concentration by 95.6% in a 30-patient IRB study and yielded a 37.2% mean hair density reduction at 90 days compared to 26.7% on the control side. Pain scores were 31% lower (3.5 vs 5.1) on treated sites with no adverse events reported.

1. Clinical Trial Results

In a randomized, single-center IRB study of 30 subjects, the hydrogel patch reduced laser plume concentration by 95.6% (p=0.0001) and delivered a 37.2% mean hair density reduction at 90 days versus 26.7% for the control side (p=0.3607).

2. Safety and Efficacy Outcomes

Treated sites reported mean pain scores of 3.5 versus 5.1 on control sites (p=0.0033) and no adverse events were observed, indicating an improved patient and practitioner experience during laser hair removal procedures.

3. Strategic and Commercial Implications

Funded by Innovative Optics, the trial addresses airborne laser plume hazards and positions NEXGEL for potential adoption under emerging plume management regulations, supporting expansion of its medical device portfolio and future commercialization plans.

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