Niagen Bioscience reports analysis finds Niagen NR cuts muscle epigenetic age by about 2.5 years in 5-month trial

Niagen Bioscience said a newly published peer-reviewed analysis in Aging Cell re-examined prior human trials of its Niagen nicotinamide riboside supplement.

• The results had already been generated in earlier studies; the new analysis was published now rather than being slated for a future scientific presentation.
• The review found supplementation was associated with improvements in a muscle-focused biological aging marker, supporting a healthier muscle-aging profile.
• Findings were mixed across different biological aging tests, pointing to a nuanced effect rather than a uniform shift across all measures.
• The analysis also linked changes in muscle mitochondrial biology with shifts in the aging marker, adding support for a mechanistic rationale.