Oncolytics reports about 15-month median response duration for pelareorep combination in anal cancer trial
ONCY•Oncolytics Biotech reported updated GOBLET trial results for pelareorep with atezolizumab in previously treated advanced squamous cell anal cancer, including a median response duration of about 15 months.
1. Updated trial results
Oncolytics Biotech reported that responses to pelareorep combined with atezolizumab lasted longer than historical results for FDA-approved retifanlimab monotherapy. The company said the findings support further development of the combination.
2. Potential next studies
Following FDA Fast Track designation, additional studies with a potential checkpoint inhibitor partner could support registration, including possible accelerated approval. A similar combination study in HPV-associated head and neck cancer is under consideration.




