TG Therapeutics gains as subcutaneous BRIUMVI Phase 3 enrollment completes
TG Therapeutics shares rose after the company said it finished enrolling its Phase 3 trial of a subcutaneous version of BRIUMVI for relapsing multiple sclerosis. The update keeps the company on track to deliver top-line data around year-end 2026 or in Q1 2027, reinforcing the long-term growth story for BRIUMVI.
1. What’s moving the stock
TG Therapeutics (TGTX) is trading higher as investors react to a key development milestone for BRIUMVI: the company completed enrollment in its Phase 3 trial evaluating a subcutaneous formulation in relapsing forms of multiple sclerosis. The milestone supports confidence that TG can expand BRIUMVI beyond the current IV-only regimen and potentially unlock a more convenient, self-administered option for patients. (globenewswire.com)
2. Why the milestone matters
The Phase 3 study compares subcutaneous BRIUMVI dosing every 8 weeks or every 12 weeks versus the currently approved IV dosing schedule, with a primary goal of showing non-inferior drug exposure versus IV at week 24. If successful, the subcutaneous program could broaden use by enabling more flexible administration, including a potential at-home option—an important differentiator in a competitive anti-CD20 multiple sclerosis landscape. (globenewswire.com)
3. Timeline and what to watch next
TG expects to report top-line results around year-end 2026 or in the first quarter of 2027, putting the next major data readout squarely on the medium-term horizon rather than the near term. Investors will also watch for additional BRIUMVI clinical and commercial updates around the upcoming neurology conference calendar, where the company has indicated scheduled scientific presentations in late April 2026. (globenewswire.com)