TransMedics Group has signed a 15-year lease for a 200,000-square-foot global headquarters at Assembly Innovation Park in Somerville, Massachusetts, and simultaneously purchased the adjacent 25-acre parcel to develop a unified campus. The combined 225 acres will integrate corporate offices, R&D laboratories and advanced manufacturing, positioning TransMedics to consolidate its current operations in Andover and drive synergies across its product development lifecycle. The lease commences in January 2028, with tenant improvement allowances exceeding $20 million to customize the space for organ preservation technology workflows.

The purpose-built, Class A facility will house clinical perfusion suites, bioprocessing lines for the Organ Care System (OCS) platform and collaborative research centers. With direct adjacency to MIT, Harvard Medical School and a network of seven transplant centers within ten miles, the campus is designed to attract up to 1,000 scientists, engineers and clinical liaisons by 2030. TransMedics anticipates reducing employee turnover by 15% through on-site amenities, including a dedicated clinical training center and 50,000 square feet of co-working labs for academic partnerships.

The Massachusetts Life Sciences Center has proposed an incentive package of $18 million in performance-based tax credits—up to $30,000 per net new full-time job—contingent on creating 600 roles between 2026 and 2031. Complementary workforce grants totaling $5 million will underwrite technician training programs in collaboration with Somerville community colleges. The City of Somerville will provide $18 million in tax increment financing over ten years, expected to generate $75 million in local tax revenues. These incentives reduce capital intensity and lower breakeven timelines for TransMedics’ scaling of OCS production.

By situating its global headquarters within Boston’s life sciences corridor, TransMedics solidifies its access to a $70 billion regional biotech market and the nation’s largest pool of FDA-cleared medtech suppliers. Governor Maura Healey and Lt. Governor Kim Driscoll hailed the move as reinforcing Massachusetts’ leadership in next-generation transplant therapy. BioMed Realty’s campus development offers 30-foot ceiling heights and 300-kilowatt power resilience for continuous organ perfusion testing. TransMedics CEO Waleed Hassanein, M.D., cited proximity to a 60-member transplant physician advisory board as a key driver for accelerated clinical validation of the next-generation OCS Heart, Lung and Liver modules.