Twilio (TWLO) is trading higher in Wednesday’s session (April 8, 2026) as investors continue to react to a fresh bullish analyst reset: Jefferies upgraded the stock to Buy from Hold and raised its price target to $160 (from $125). The upgrade has helped lift sentiment around Twilio’s turnaround narrative and its positioning as an infrastructure provider for AI-driven customer engagement.

The Jefferies view centers on Twilio’s growing role in Voice AI, arguing the company’s product stack can capture incremental call volumes and monetization as more enterprises deploy AI agents in contact centers and outbound workflows. Jefferies also outlined a longer-term voice revenue opportunity that includes a meaningful Voice AI component by 2028, supporting a higher valuation framework if execution and adoption trends hold.

After an upgrade-led move, traders typically look for follow-through via additional analyst actions, management commentary, or product/customer signals that validate the Voice AI adoption curve. Investors will also focus on whether Twilio can sustain profitability and free-cash-flow momentum while funding AI-related product investments, as the market increasingly prices the stock on cash generation and durable growth rather than pure revenue expansion.