Waters Debuts OmniDAWN MALS Detector with 4× Faster Runs and 10× Mass Range
Waters Corporation launched the omniDAWN MALS Photometer, an 18-angle detector extending UPLC-compatible sizing from approximately 50 to 500 nm and delivering 10-fold molar mass improvements without resolution loss. The system achieves up to 4× faster run times, reduces sample use by 30–50% and cuts solvent consumption by about 40%.
1. Product Launch and Specifications
Waters introduced the omniDAWN Multi-Angle Light Scattering Photometer featuring 18 detection angles for UHPLC/UPLC systems. This detector extends sizing capability from approximately 50 to 500 nm in radius and delivers a tenfold improvement in absolute molar mass measurement without compromising resolution or analytical throughput.
2. Performance Advantages
When paired with UHPLC or UPLC workflows, the omniDAWN Photometer supports run times up to four times faster than conventional HPLC methods. Its low-dispersion design preserves sensitivity while reducing sample consumption by 30–50% and cutting solvent use by around 40%, streamlining high-throughput analyses.
3. Integration and Applications
The detector integrates seamlessly with Waters’ UPLC systems and columns, eliminating trade-offs between dispersion and performance. It enables absolute molar mass and size measurements for complex analytes—such as protein aggregates, viral vectors, ADCs and LNPs—without reliance on calibration standards.
4. Market Impact and Availability
Powered by ASTRA software and compliant with 21 CFR Part 11 and EU Annex 11, omniDAWN will be globally available in summer 2026. Its adoption is set to accelerate discovery, development and quality control workflows in biopharmaceutical and advanced materials laboratories.