AbbVie Raises 2026 Outlook to $14.28, Triggers $18M Oncology Milestone

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AbbVie posted Q1 adjusted EPS of $2.65 with $15B revenue, topping forecasts and raising its 2026 outlook to $14.28 per share. The company triggered an $18M preclinical oncology milestone payment under its EvolveImmune collaboration and saw immunology sales hit $7.29B led by Skyrizi.

1. Q1 Financial Performance

AbbVie delivered Q1 adjusted EPS of $2.65 and revenue of $15.0B, each exceeding consensus estimates. Strong market share gains in immunology and neuroscience underpinned the beat, with immunology sales reaching $7.29B led by Skyrizi’s leadership in psoriatic disease.

2. Upgraded 2026 Guidance

Following the better-than-expected quarter, management increased its full-year adjusted EPS outlook to $14.28 per share, up 12 cents from prior guidance. The revision reflects confidence in newer growth drivers offsetting Humira declines.

3. Oncology Collaboration Milestone

AbbVie achieved a preclinical milestone in its EvolveImmune Therapeutics partnership, nominating a solid tumor development candidate and triggering an $18M milestone payment. This advancement underscores progress in AbbVie’s oncology pipeline and collaboration strategy.

Sources

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