Abivax to Showcase Nine Obefazimod Abstracts Including Dual Anti-Fibrotic Data at DDW

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Abivax will present nine scientific abstracts on obefazimod at Digestive Disease Week May 2-5, showcasing Phase 3 ABTECT program data on efficacy, safety and patient-reported outcomes in moderately to severely active ulcerative colitis. Presentations also include preclinical models demonstrating obefazimod’s dual anti-inflammatory and anti-fibrotic activity.

1. Presentation Details

Abivax will unveil nine abstracts on obefazimod at Digestive Disease Week 2026 in Chicago from May 2 to 5, covering clinical and preclinical findings.

2. Phase 3 ABTECT Highlights

Abstracts from ABTECT-1 and ABTECT-2 include efficacy, safety, histologic and endoscopic outcomes and subgroup analyses in patients with moderately to severely active ulcerative colitis.

3. Patient-Reported Outcomes

Data will show early symptomatic improvements in fatigue and quality-of-life metrics from pooled induction trial results.

4. Preclinical Anti-Fibrotic Findings

Two presentations describe obefazimod’s anti-fibrotic effects in murine fibrosis models and its modulation of inflammatory cytokines and mir-124 expression in human tissues.

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