Apogee Therapeutics Attracts $95 Target Suggesting 37% Upside, RBC Hikes To $83

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Citi maintained its Buy rating on Apogee Therapeutics with a $95 price target, forecasting over 37% upside and deeming the post-Sanofi Phase 3 selloff an overreaction given APG279’s prospects. RBC Capital lowered its rating to Sector Perform but boosted its target to $83, implying roughly 20% upside.

1. Diverging Analyst Ratings

Citi maintained its Buy rating on Apogee Therapeutics with a $95 price target, anticipating more than 37% upside, while RBC Capital lowered its rating to Sector Perform yet raised its target to $83, implying roughly 20% potential gains.

2. Meacham Defends APG279 Value

Geoff Meacham views the post-Sanofi Phase 3 amlitelimab selloff as an overreaction and underscores the potential of APG279, a fixed-dose IL-13 and OX40L combination, as key to the company’s inflammatory disease strategy.

3. RBC Notes Market Crowding

RBC analyst Brian Abrahams highlighted intensifying competition in the IL-13 atopic dermatitis segment and pointed to a 108% share rally over the past year as factors limiting further upside.

4. Broad Clinical Pipeline

Apogee’s pipeline includes APG279, zumilokibart (long-acting IL-13 for atopic dermatitis), and additional candidates APG777, APG990, APG333 and APG808, addressing asthma, COPD, eosinophilic esophagitis and other immune diseases.

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