Certara posted revenue of $103.6 million in Q4 2025, up 3% year-over-year on a reported basis and 2% on a constant currency basis. Software revenue rose 10% to $46.4 million while services declined 1% to $57.3 million. Adjusted EBITDA decreased 3% to $32.5 million and net loss widened to $5.9 million from $6.6 million net income a year earlier.

For fiscal 2025, Certara generated revenue of $418.8 million, marking 9% growth, with adjusted EBITDA of $134.5 million up 10%, resulting in a 32% EBITDA margin. The company sustained investments in R&D and achieved operating efficiencies while service bookings climbed 7% to $155.2 million.

Certara forecasts full-year 2026 revenue growth of 0–4% with an adjusted EBITDA margin of 30–32% and adjusted diluted EPS between $0.44 and $0.48. Management expects stable end markets and plans strategic investments in innovation and commercial execution to drive growth through the year.

Jon Resnick assumed the role of CEO on January 1, 2026, with a mandate to sharpen strategic focus, accelerate product portfolio innovation, and elevate go-to-market execution. The company will implement organizational changes and process enhancements in 2026 to capture market opportunities and support sustainable long-term growth.