Codexis to Reveal Improved Stereochemistry Control, Ligation Efficiency at TIDES USA
Codexis will present advances in its ECO Synthesis Manufacturing Platform for siRNA at TIDES USA May 11–14 in Boston, showcasing improved phosphorothioate stereochemistry control and enhanced ligation efficiency. Experts will deliver three presentations and a stereochemistry panel May 12–14, highlighting regulatory progress and scalability of high-quality RNAi production.
1. TIDES USA Participation
Codexis will showcase its enzymatic ECO Synthesis Manufacturing Platform at TIDES USA in Boston from May 11–14, highlighting the company’s role in scalable RNAi therapeutic production. The presence includes presentations, booth engagement, and a specialized panel discussion supporting industry dialogue on stereochemical control.
2. ECO Synthesis Manufacturing Advances
The platform improvements feature enhanced control over phosphorothioate stereochemistry and improved ligation efficiency in siRNA manufacturing, aiming to deliver higher yields and product quality. Codexis emphasizes sustainability benefits through reduced energy usage and waste generation compared to traditional oligonucleotide synthesis routes.
3. Presentation Schedule
Technical experts will present three sessions: a spotlight on stereochemistry challenges on May 14, a TIDES Talk on scalable ligation solutions on May 13 morning, and a conference presentation on sustainability innovations on May 13 afternoon. Each session underscores platform performance and regulatory engagement progress.
4. Expert Panel on Stereochemistry
On May 12, Codexis will host a panel titled "Stereochemistry in RNAi Manufacturing: Signal or Noise?" featuring industry leaders discussing the implications of stereochemical control for therapeutic performance and manufacturing options.