Ipsen Secures Global Rights to SIM0613 ADC Expanding Early-Stage Pipeline

IPSEYIPSEY

Ipsen has secured exclusive global rights (excluding Greater China) for SIM0613, a LRRC15-targeting antibody-drug conjugate from Simcere Zaiming. The deal encompasses development, manufacturing and commercialization, bolstering Ipsen’s early-stage oncology pipeline.

1. Ipsen Secures Exclusive Global Rights to SIM0613 ADC

On December 15, 2025, Ipsen (ADR: IPSEY) announced that it has acquired exclusive global development, manufacturing and commercialization rights for SIM0613, a LRRC15-targeting antibody-drug conjugate licensed from Simcere Zaiming. Under the agreement, Ipsen will lead all clinical development activities outside Greater China, with first-in-human studies expected to commence in mid-2027. The deal adds a novel modality to Ipsen’s oncology pipeline, increasing its early-stage programme count to 12 candidates across five tumour targets. Ipsen has committed up to $60 million in upfront and milestone payments and will finance all subsequent R&D costs, in exchange for tiered low-double-digit royalties on net sales. This strategic acquisition reinforces Ipsen’s position in targeted cytotoxic therapies and underpins its goal to launch two new oncology assets by 2030.

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