Neurocrine to Acquire Soleno Therapeutics for $2.9B at 34% Premium

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Soleno Therapeutics agreed to be acquired by Neurocrine Biosciences at $53 a share, valuing the deal at about $2.9 billion and representing a 34% premium to the April 2 closing price. Its Vykat XR generated $190 million in revenue in 2025, bolstering Neurocrine’s strategic leadership in endocrinology and rare-disease therapies.

1. Acquisition Agreement Details

Neurocrine Biosciences will acquire Soleno Therapeutics for $53 per share in cash, valuing the transaction at approximately $2.9 billion. The deal is structured as a tender offer via a subsidiary and is expected to close within about 90 days, subject to customary conditions and regulatory approvals.

2. Premium and Valuation Implications

The $53 offer represents a 34% premium to Soleno’s closing share price on April 2 and a 51% premium to its 30-day volume-weighted average price. Shares of Soleno rallied 56.4% over the past week and are up 13.1% year to date, reflecting strong investor sentiment toward the deal.

3. Vykat XR Contribution and Strategic Fit

Soleno’s Vykat XR generated $190 million in 2025 as the first FDA-approved treatment for hyperphagia in Prader-Willi syndrome. The acquisition enhances Neurocrine’s rare-disease portfolio and leverages its commercial infrastructure and intellectual property extending into the mid-2040s to drive long-term value.

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