State Street Health Care ETF Outpaces Invesco Pharma ETF on Cost and Scale
IVZ•State Street Health Care Select Sector SPDR ETF offers a significantly lower expense ratio and manages far more assets than the Invesco Pharmaceuticals ETF. Invesco’s fund holds 29 pharmaceutical companies, while the SPDR fund provides broader exposure across the entire healthcare sector.
1. Expense Ratio Comparison
The State Street Health Care Select Sector SPDR ETF charges a markedly lower expense ratio than the Invesco Pharmaceuticals ETF, making it more cost-efficient for investors seeking healthcare exposure.
2. Assets Under Management
The SPDR fund manages substantially more assets than Invesco’s ETF, reflecting broader institutional demand and higher liquidity relative to the smaller Invesco Pharmaceuticals offering.
3. Portfolio Scope Differences
Invesco’s ETF focuses exclusively on 29 pharmaceutical companies, whereas the SPDR fund spans the full healthcare sector, including pharmaceuticals, services, equipment, and biotechnology.





