Twilio jumps nearly 5% as Mizuho lifts target to $165, fueling momentum bid

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Twilio shares rose 4.69% on April 22, 2026 to about $152.20 after an analyst upgrade and fresh price-target lift helped extend recent momentum. Mizuho boosted its target to $165 and reiterated an outperform stance, while investors continue to focus on Twilio’s improving profitability and growth re-acceleration narrative.

1. What’s moving the stock today

Twilio (TWLO) is higher today as investors react to bullish analyst action that lifted near-term sentiment. Mizuho raised its price target to $165 and kept an outperform-style rating, helping push the stock to fresh 52-week highs in the session and driving incremental buying interest from momentum and event-driven traders. (defenseworld.net)

2. The broader analyst reset that’s supporting the move

Today’s upgrade-driven move comes alongside other recent Street actions that have been raising the ceiling on Twilio’s valuation as investors lean into a profitability-and-growth recovery story. Earlier this week, Oppenheimer lifted its price target to $160 from $90 and maintained an Outperform rating, citing improved confidence following Twilio’s Investor Day and pointing to operational efficiency gains and go-to-market execution as key supports for further upside. (tipranks.com)

3. What investors will watch next

With the stock now trading near the upper end of several updated targets, the next leg higher will likely depend on confirmation that demand is firm and that margin discipline holds. Investors are focused on signs of sustained revenue growth acceleration, continued operating leverage, and whether Twilio can keep translating product momentum into durable free-cash-flow generation as 2026 expectations reset higher.