On the Chinese side, the talks could be led by Vice Premier He Lifeng, Bessent's protocol counterpart, but alternatives such as China's number seven official Ding Xuexiang may be considered, according to the second source, who also spoke on condition of anonymity.
Ding, a confidant of Xi and a member of the ruling Communist Party's powerful seven-person Politburo Standing Committee, coordinates China's technology, AI and semiconductor policies.
Reuters could not determine the location or identity of other participants, though Kratsios and China's science and technology minister, Yin Hejun, could attend the talks, the second source added.
The final agenda and participants remain in flux, the sources cautioned.
The White House declined to comment on the AI talks. A U.S. Treasury spokesperson said the two sides "may meet in October" about the technology. The State Department did not respond to a request for comment. China's foreign, science and industry ministries, as well as the National Development and Reform Commission and cyberspace regulator, did not immediately respond to requests for comment.
On Tuesday, Kratsios told reporters in North Carolina that he had a "great" meeting with Yin on the sidelines of a G20 innovation summit in the U.S. this week. Bessent said he had "limited" exchanges on AI with Chinese officials at this week's G20 finance meeting.
The U.S. urged G20 members to take a hands-off approach to AI regulation and avoid creating rules for the technology at the same innovation summit. China signed the Carolina Principles, an agreement aimed at discouraging the development of AI-specific regulations, in a rare show of tech alignment with the U.S.
Chinese officials have repeatedly stressed the importance of the AI talks in preparatory meetings with U.S. counterparts, and view them as a major deliverable of the U.S.-China leaders' summit, according to the two sources and another one familiar with the matter. Reuters is reporting this development for the first time.
In the past week, China's cyberspace regulator publicly warned about "extreme AI loss of control risks" and a state media-affiliated blog criticized Anthropic, emphasizing that any limits on frontier AI should apply equally to Chinese and U.S. models. Chinese firms have in recent months unveiled what they describe as Mythos-like products.
Former Microsoft executive Craig Mundie has emerged as an important go-between behind the scenes, sounding out Chinese counterparts on U.S. proposals for the AI dialogue, the source said. Mundie is co-chair of the unofficial U.S.-China Track II AI dialogue channel.
Reuters reported last month that Microsoft had cultivated a relationship with Beijing that was among the deepest of any foreign technology company operating in China.
Both sides also discussed AI guardrails at a Track 1.5 dialogue in Beijing last week, former Australian Prime Minister Kevin Rudd, a participant, wrote on social media.
In June, Trump signed an AI executive order setting up a voluntary framework for pre-release cybersecurity reviews of frontier AI models, but the U.S. has not released the criteria for these reviews.
Meanwhile, employees at top U.S. AI labs including Anthropic and OpenAI have called for "pacing the frontier" to manage the global risks of advanced AI.
"The Chinese side has expressed concern around whether the U.S. has sufficient regulation around the most advanced AI models. Both sides are motivated to make sure they can manage a cross-border crisis effectively," said Scott Singer, co-director of the China AI Initiative at the Carnegie Endowment for International Peace.
While outcomes are likely to be limited, opening a channel where both sides could share observations and jointly monitor AI safety incidents would be an important starting point, said Samm Sacks, a senior fellow at New America, a U.S. policy think tank.
"We are at a tipping point where frontier agents can cause massive damage when unmonitored. Both the U.S. and China are vulnerable. This is beyond geopolitical rivalry," Sacks added.
"The U.S. and China have to come together in some form, or we're both going to lose."