Does Rallies show 13F holders for SPRO?

Yes. Rallies tracks hedge fund and 13F ownership data for SPRO, including fund names, share counts, latest tracked quarter, and position changes when available.

Is SPRO research on Rallies investment advice?

No. Rallies provides research, data, and educational context for SPRO. It does not provide personalized investment advice.

SPRO (Spero Therapeutics, Inc. Common Stock) Stock Analysis - Hedge Fund Holdings

Spero Therapeutics, Inc. Common Stock (SPRO) is a publicly traded Healthcare sector company. As of May 21, 2026, SPRO trades at $2.60 with a market cap of $149.39M and a P/E ratio of 0.00. SPRO moved +1.16% today. Year to date, SPRO is +8.23%; over the trailing twelve months it is +286.65%. Its 52-week range spans $0.51 to $3.22. Rallies surfaces SPRO's financials, insider trades, hedge fund holdings, congressional trades, analyst ratings, and AI-generated research below.

Who owns SPRO stock?

Hedge funds tracked by Rallies that own SPRO include Renaissance Technologies, Citadel Advisors, and Two Sigma. The latest tracked quarter is Dec 31, 2024. Rallies shows current holdings, share counts, position changes, and 13F ownership context for Spero Therapeutics, Inc. Common Stock.

SPRO Key Metrics

Key financial metrics for SPRO
Metric	Value
Price	$2.60
Market Cap	$149.39M
P/E Ratio	0.00
EPS	$0.00
Dividend Yield	0.00%
52-Week High	$3.22
52-Week Low	$0.51
Volume	0
Avg Volume	0
Revenue (TTM)	$13.51M
Net Income	$-525.95K
Gross Margin	57.80%

Top Hedge Funds Holding SPRO

Renaissance Technologies holds 1.11M shares of SPRO, changed +13.43% as of Dec 31, 2024.
Citadel Advisors holds 167.60K shares of SPRO, changed +114.42% as of Dec 31, 2024.
Two Sigma holds 67.73K shares of SPRO, changed +557.49% as of Jun 30, 2024.

Latest SPRO News

Spero Therapeutics’ Q1 Loss Narrows to $7.2M as PDUFA Date Set June 18 — May 13, 2026
Spero Reports $31.5M Q4 Net Income and Resubmits tebipenem HBr NDA for June Decision — Mar 26, 2026

Recent SPRO Insider Trades

Rajavelu Esther sold 25.24K (~$63.35K) on May 4, 2026.
Rajavelu Esther sold 37.10K (~$87.56K) on Feb 6, 2026.
Rajavelu Esther sold 50.82K (~$119.93K) on Feb 6, 2026.

SPRO Analyst Consensus

SPRO analyst coverage data. Average price target: $0.00.

Common questions about SPRO

Who owns SPRO stock?: Hedge funds tracked by Rallies that own SPRO include Renaissance Technologies, Citadel Advisors, and Two Sigma. The latest tracked quarter is Dec 31, 2024. Rallies shows current holdings, share counts, position changes, and 13F ownership context for Spero Therapeutics, Inc. Common Stock.
Does Rallies show 13F holders for SPRO?: Yes. Rallies tracks hedge fund and 13F ownership data for SPRO, including fund names, share counts, latest tracked quarter, and position changes when available.
Is SPRO research on Rallies investment advice?: No. Rallies provides research, data, and educational context for SPRO. It does not provide personalized investment advice.