Amazon Launches GLP-1 Program at $25/$149, Rufus AI Hits 300M Users

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Amazon One Medical launched a GLP-1 management program charging $25 with insurance or $149 cash and offering next-day delivery to simplify access. Amazon's AI-driven Rufus assistant attracted 300 million users in 2025 with a 60% higher conversion rate and added scheduled actions for automated item replenishment.

1. GLP-1 Program Launch

Amazon One Medical’s new GLP-1 management program offers popular weight-loss and diabetes therapies at $25 with insurance or $149 for cash-paying patients. The initiative leverages Amazon’s one-day delivery network to streamline prescriptions and compete with established specialty pharmacies.

2. Rufus AI Expansion

Amazon’s Rufus shopping assistant reached 300 million users in 2025, driving a 60% higher purchase rate among participants. The latest update enables scheduled actions for automated replenishment of everyday items and gift selection based on past behavior, positioning Amazon to capture incremental e-commerce revenue.

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