Royalty Pharma buys cliramitug royalty stake from Neurimmune for up to $425 million
RPRX•Payment terms and development timeline
Another $125 million cash payment is due in Q1 2027; the remaining $175 million is tied to clinical and regulatory milestones.
Phase 3 DepleTTR-CM trial results are expected in 2028; AstraZeneca has guided to $3 billion to $5 billion peak sales.
Royalty Pharma acquires royalty interest in AstraZeneca’s cliramitug
Royalty Pharma acquired part of Neurimmune’s royalty interest in AstraZeneca’s cliramitug for up to $425 million, including $125 million upfront.
The deal grants a 3% to 4% royalty on worldwide net sales of cliramitug, a Phase 3 antibody for ATTR-CM.




