VivoSim Labs plans rat liver model expansion for NAMkind platform
VIVS•VivoSim Labs plans rat liver model expansion
- VivoSim Labs plans to develop a rat liver model to expand its NAMkind human liver platform for preclinical liver toxicology.
- Paired rat-human models target species-translation risk, helping assess whether rat liver findings are relevant to humans.
- Validation will use compounds with known rat-human differences in liver toxicity.
- The strategy aims to reduce premature program termination and improve decision-making on advancing or modifying drug candidates.
